Classification of Alzheimer Disease based on Normalized Hu Moment Invariants and Multiclassifier

There is a great benefit of Alzheimer disease (AD) classification for health care application. AD is the most common form of dementia. This paper presents a new methodology of invariant interest point descriptor for Alzheimer disease classification. The descriptor depends on the normalized Hu Moment Invariants (NHMI). The proposed approach deals with raw Magnetic Resonance Imaging (MRI) of Alzheimer disease. Seven Hu moments are computed for extracting images’ features. These moments are then normalized giving new more powerful features that highly improve the classification system performance. The moments are invariant which is the robustness point of Hu moments algorithm to extract features. The classification process is implemented using two different classifiers, K-Nearest Neighbors algorithm (KNN) and Linear Support Vector Machines (SVM). A comparison among their performances is investigated. The results are evaluated on Alzheimer’s Disease Neuroimaging Initiative (ADNI) database. The best classification accuracy is 91.4% for KNN classifier and 100% for SVM classifier. Keywords—Alzheimer disease; machine learning; Hu moment invariants; SVM; K-Nearest Neighbors (KNN) classifier